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METRONIDAZOL


METRONIDAZOL 
 

Chemical Name: 2-Methyl-5-Nitroimidiazole-1-Ethanol

Trade Names:  METRONIDAZOL

General Applications:

Metronidazole is used to treat parasitic infections including Giardia infections of the small
intestine, amebic liver abscess and amebic dysentery (infection of the colon causing bloody
diarrhea), bacterial vaginosis, trichomonas vaginal infections, and carriers of trichomonas (both
sexual partners) who do not have symptoms of infection. Metronidazole is also used alone or in
combination with other antibiotics in treating abscesses in the liver, pelvis, abdomen and brain
caused by susceptible anaerobic bacteria.

 

Introduction:
Metronidazole is a nitroimidazole anti-infective medication used mainly in the treatment of
infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa.

 

TEST STANDARD Unit Ref
IR spectra Spectrum obtained with standard Metronidazole USP41-NF36
Organic Impurities —Tinidazole Compound A NMT 0.1

 

 

— Any single unspecified  Impurity  NMT 0.1

 

—Total Impurities NMT 0.2

%wt USP41-NF36
Loss on drying Max 0.5 %wt USP41-NF36
Residue on Ignition Max 0.1 %wt USP41-NF36
Assay 99 – 101 %wt USP41-NF36
Heavy  metals Max 50 ppm USP41-NF36
Residual solvents Defined as Organic  volatile chemicals ppm USP41-NF36

Packaging Type

Net weight

Gross weight

No. of drums per pallet

No. of pallets in a 20 FLC

Shelf life

IMCO Class

  PE bags in Paper Drums

25 Kgs

40 Kgs

6

20

2 yrs

Non-Imco

Safety, Handling & Storage:
  Full information on the safety, handling and storage of KECASs is available in the corresponding Material Safety Data Sheet (MSDS).

 

 
 
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